Vol 34(2018) N 2 p. 47-53; DOI 10.21519/0234-2758-2018-34-2-47-53
D.A. Lukianov*, and V.G. Debabov

Obtaining of Succinic Acid and Higher Alcohols (C810) Diesters by Method of Biphasic Esterification

The State Research Institute for Genetics and Selection of Industrial Microorganisms of National Research Center "Kurchatov Institute ", 117545, Moscow Russia

Received - 30.01.2018; Accepted - 15.02.2018


A process of biphasic esterification by higher alcohols (С810) of model aqueous solutions of crystalline succinic acid or culture liquid obtained as a result of growing of a succinic acid producer has been investigated. The main part of the work was performed using isooctyl (2-ethylhexyl) alcohol. Laurylsulfonic acid (another name dodecylsulfonic acid) was introduced as a catalyst. It was shown that the yield of diesters increases with growing ratio alcohol/succinic acid solution and it is superior to 90% when the ratio is 2:1. At the constant ratio of the above phases, the product yield is enhanced with decreasing concentration of succinic acid in the aqueous solution. More than 10% of the DSA catalyst passes into the alcohol phase; the compound can be extracted by the Na2CO3 solution. The application of real culture liquid results in a significant decrease in the product yield as compared to the model succinic acid solutions. The process can become industrially promising after the selection of other efficient catalysts and improvement of the microbial fermentation to provide the decrease in organic acid content in the culture liquid.

succinic acid, esterification, dodecylsulfonic acid

Acknowledgements-The authors are acknowledged to Yu.V. Skvorniakov (LLC Globalkhimfarm), S.B. Gomboeva (LLC Globalkhimfarm) and P.Yu. Bondarenko (NRC "Kurchatov Institute" -GOSNIIGENETIKA) for the analytical support of the work.